Carences en folates (vitamine B
Folate metabolism (vitamin B
Cette revue fait la synthèse des récentes connaissances sur les carences en folates et leur impact sur la santé humaine. La carence en folates (vitamine B
Folate deficiency is a major concern in terms of public health across the world. Limited access to food resources and poverty accentuate this problem in southern countries. Folate is involved in the synthesis of nucleic acids (ADN, ARN), methylation processes and control of the rate of homocysteine synthesis. Consequently, folate deficiency is associated with crippling and lethal foetal abnormalities, risk of cancer and vascular and neurological disorders. In addition to dietary folate deficiency, environmental factors (food contaminants, alcohol), infectious diseases (malaria) and genetic determinants of folate metabolism are predictive factors that need to be taken into account in public health policies in Africa.
Cancer, Contaminant alimentaire, Folates, Homocystéine, Génétique, Vitamines B, Santé publique
Cancer, Food contaminant, Folate, Homocysteine, Genetics, Vitamins B, Public health